Review
Open access
Aug 2026
Optimization of DMH-Induced Colorectal Carcinogenesis in Rats: A Systematic Meta-Review
Abstract Colorectal cancer (CRC) remains a major global health concern, and experimental animal models continue to play a key role in understanding its development and in evaluating preventive and therapeutic strategies. Among these, the 1,2-dimethylhydrazine (DMH)-induced rat model is widely used; however, substantial...
Alireza Salehi, F. Yaghoobi, Mostafa Kami et al.
· Clinical and Experimental Ga... · 0 citations