Author

Hamel Mahiou

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Open access Aug 2026

Generation and characterization of three human induced pluripotent stem cell lines from patients with Duchenne muscular dystrophy.

Three induced pluripotent stem cell lines reprogrammed from peripheral blood mononuclear cells (PBMCs) of patients with DMD constitute a relevant human cellular model for studying disease-associated phenotypes and evaluating potential therapeutic strategies.

Hamel Mahiou, Benjamin Marande, L. Kassar et al. · Stem Cell Research · 0 citations

Open access Jul 2026

Cortical organoids from congenital DM1 PSCs reveal MBNL-dependent corticogenesis defects and enable preclinical testing of therapeutic compounds

Cortical organoids are established as a robust human model of CDM-associated neurodevelopmental defects, uncover MBNL-dependent mechanisms underlying early corticogenesis impairment and demonstrate the utility of this platform for translational therapeutic discovery in DM1.

Azania Abatan, Jérôme Polentes, M. Bouquier et al. · bioRxiv · 0 citations