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Author

Haleema Ahmad

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Open access Sep 2026

BRIP1, a G-quadruplex DNA helicase, protects against AID-induced genomic instability by limiting R-loop accumulation

BRIP1 (BRCA1-interacting protein 1) or FANCJ is a 5′–3′ DNA helicase that plays critical roles in the maintenance of genome stability through its involvement in DNA repair, replication stress responses, and the resolution of DNA secondary structures or non-B DNAs. Defects in the BRIP1 helicase gene are associated with...

Aisha Mahboob, Haleema Ahmad, Nishat Fatma et al. · 0 citations

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