Haiwei Ji

Employing pH/reactive oxygen species (ROS) dual-responsive chitosan/oxidized dextran composite hydrogels based on dual-dynamic bonding to enhance regeneration and repair in diabetic wounds.

This integrated strategy successfully addresses major challenges in diabetic wound treatment-namely, susceptibility to infection, persistent inflammation, elevated oxidative stress, and impaired angiogenesis by enabling synergistic regulation of antibacterial, anti-inflammatory, antioxidant, and pro-regenerative effects.