Open access
Sep 2026
Epstein-Barr virus gp350 neutralizing epitopes define distinct sites of vulnerability.
Epstein-Barr virus (EBV) is a widespread human herpesvirus linked to several malignancies, yet no vaccine has been approved. Its major surface glycoprotein, gp350, mediates attachment to B cells via CR2 binding, but gp350-based vaccines have shown limited protection, raising questions about its neutralizing epitopes an...
Ge-Xin Zhao, Peng-Lin Li, Bo-Yu Yuan et al.
· Cell Reports · 0 citations