Preparation and functional evaluation of an alginate-targeted monoclonal antibody against Pseudomonas aeruginosa.
Pseudomonas aeruginosa is a critical-priority pathogen responsible for life-threatening infections in immunocompromised individuals, yet its extensive antigenic heterogeneity has impeded the development of immunotherapeutics. Alginate, a structurally conserved surface polysaccharide that forms the backbone of the biofi...