A lactate-fatty acid loop drives prostate cancer bone colonization by mediating metabolic interplay between tumor cells and osteoblasts
Bone metastases (BoM) develop in 60–90% of men with advanced prostate cancer (PCa) and are associated with a significantly decreased quality of life and 5-fold increased risk of mortality. However, current frontline treatments offer only marginal improvements in survival and symptom management. In this study, we invest...
Hai Wang
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