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Hai-Ting Duan

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#machine learning Open access Aug 2026

AI-driven PROTAC design overcomes oncogenic resilience by eliminating the CLIP1-LTK fusion protein.

The AI-guided development of a first-in-class proteolysis-targeting chimera (PROTAC) designed to selectively degrade the CLIP1-LTK fusion protein is reported, providing a promising therapeutic strategy for overcoming acquired resistance in kinase-driven cancers.

Shi-Cheng Chen, Hai-Ting Duan, S. Zhong et al. · 0 citations

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