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Hai-Tao Shi

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Open access Sep 2026

Causal effects of gut microbiota on functional gastrointestinal disorders: a bidirectional Mendelian randomization study.

Emerging evidence suggests that gut microbiota is associated with functional gastrointestinal disorders (FGIDs). However, findings regarding microbial alterations in FGIDs have been inconsistent across observational studies, and the direction and causality of these associations remain unclear. We conducted a bidirectio...

Yu-Tong Cheng, Qiu-Ai Shu, Zi-Wei Wang et al. · 0 citations
Open access Jul 2026

Exosome-mediated hepatocellular carcinoma progression by modulating macrophage metabolic reprogramming and macrophage M2 polarization via exosome-derived hsa_circ_0057320-miR-28-5p/E2F6 axis.

Exosomes derived from HOXD3-treated HCCs induced macrophage polarization toward the M2 phenotype via metabolic reprogramming, and exosomes derived from HOXD3-induced HCC cells promotes M2 macrophage polarization via metabolic reprogramming, thereby accelerating HCC malignancy.

Lu-Min Wang, Chenyang Qiao, Zhiqiang Wang et al. · 1 citation

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