Hai-Qi Liang

Dipeptidase-1 Contributes to Sepsis-Associated Endothelial Dysfunction via the EGR1/NF-κB Signaling Axis

Background Sepsis is characterized by endothelial dysfunction that contributes to vascular leakage, inflammation, and organ failure. Although metabolic enzymes are increasingly being recognized as regulators of inflammatory signaling, the role of Dipeptidase-1 (DPEP1) in endothelial dysfunction remains unclear. Methods...