Author

Haihua Pan

3 papers indexed here

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Review Open access Oct 2026

Potential roles for transient receptor potential vanilloid 1 in heart failure with preserved ejection fraction

ABSTRACT Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous syndrome in which diastolic dysfunction develops against a background of interacting mechanisms: inflammation, oxidative stress, impaired calcium homeostasis, myocardial fibrosis, coronary microvascular dysfunction, mitochondrial impairm...

Zhi-Cheng Gao, Jia-Qi Bao, Chao-Jie He et al. · Channels · 0 citations

Review Open access Sep 2026

Exerkines in Cardiovascular–Kidney–Metabolic Syndrome: An Integrative Framework for Mechanisms and Therapeutic Implications—A Narrative Review

Cardiovascular–kidney–metabolic (CKM) syndrome represents a pathophysiological continuum linking metabolic dysfunction, chronic kidney disease (CKD), and cardiovascular disease (CVD) through shared mechanisms, including insulin resistance, chronic inflammation, endothelial dysfunction, mitochondrial impairment, and mal...

Hong-Yan Fan, Chang-Lin Zhai, Chao-Jie He et al. · Reviews in cardiovascular me... · 0 citations

Review Open access Aug 2026

Post-translational modifications in sepsis-induced myocardial dysfunction - Molecular mechanisms and therapeutic targets: A review.

PTMs represent promising mechanistic and therapeutic targets in SIMD, but systematic characterization of PTM crosstalk and rigorous human translational studies are required before PTM-directed strategies can be incorporated into clinical practice.

Xuan Liu, Hai-Hua Pan, Jun Cha et al. · Biomolecules & biomedicine · 0 citations