Oct 2026
Azoreductase-Responsive Self-Assembled 10-Hydroxycamptothecin Nanofibers for Tumor-Specific Imaging and Therapy
Hypoxia is a defining feature of the tumor microenvironment (TME). The overexpression of azoreductase (AzoR) in hypoxic conditions enables it to serve as a trigger for drug release in tumor therapy. Developing a theranostic agent that is selectively activated in TME is vital for enhancing anti-tumor efficacy while mi...
Li-Song Zhang, Tian-Hang Wang, Yu-Ying Wang et al.
· Biomacromolecules · 0 citations