Hafize Uzun

Systemic inflammatory and immunonutritional profile in women with low anti-Müllerian hormone levels

in Objectives: Anti-Müllerian hormone (AMH) is widely used as a biomarker of ovarian reserve. Although systemic inflammation and nutritional status may be associated with ovarian function, the relationships of composite inflammatory and nutrition-related indices with low AMH remain incompletely characterized. This stud...

Serum NF-κB p105 and IL-17 in psoriasis: associations with disease status and severity.

Serum NF-κB p105 and IL-17 levels were significantly higher in patients with psoriasis compared to controls, and IL-17 was strongly associated with PASI, whereas NF-κB p105 remained associated with psoriasis status after adjustment for age and BMI.

Comparative Effects of Pairwise Combinations of Carboplatin, Everolimus, and Astaxanthin on Cell Viability, Migration, and Inflammatory Biomarkers in SKOV3 Ovarian Cancer Cells

Ovarian cancer remains a major cause of gynecological cancer-related mortality, highlighting the need for novel therapeutic strategies capable of enhancing antitumor activity while targeting multiple mechanisms involved in tumor progression. Everolimus, an inhibitor of the mammalian target of rapamycin pathway, and car...

The FGF23/α-Klotho Axis in Postmenopausal Osteoporosis: Associations with Bone Mineral Density and Diagnostic Discrimination

Background: Fibroblast growth factor 23 (FGF23) and α-Klotho are key regulators of mineral metabolism and bone homeostasis; however, their combined diagnostic value in postmenopausal osteoporosis remains incompletely understood. This study investigated the associations of serum FGF23, α-Klotho, and the FGF23/α-Klotho r...

Differential Effects of Carboplatin, Metformin, and Boric Acid on Cell Viability, Migration, and Oxidative Stress in MCF-7 Breast Cancer and CRL-4010 Normal Mammary Epithelial Cells

Background/Objectives: Oxidative stress is a key contributor to breast cancer (BC) progression and therapeutic response. Although carboplatin is widely used in BC treatment, the effects of combining carboplatin with metformin and boric acid (BA) on cellular redox homeostasis remain poorly understood. This study investi...

Comparative Effects of Metformin, Boric Acid, and Lithium Chloride on Oxidative Stress-Mediated Cytotoxicity in HepG2 Hepatocarcinoma Cells.

Exploratory Biological Correlates of Cognitive and Language Performance in Healthy Pubertal Children: A Retrospective Cross-Sectional Study

The study’s confirmatory finding is the FDR-significant association of PIV with age-appropriate WISC-R Verbal performance, which suggests these relationships are best interpreted within a developmental and neuroimmune framework.