Author

H. Zook

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Open access Oct 2026

Oxygen-permeable microwell plates for high-throughput spheroid culture

Oxygen (O2) transport is a major limitation in high-density cell culture, particularly as three-dimensional (3D) spheroids are increasingly used to better mimic in vivo tissue environments. Here, we developed a poly(4-methyl-1-pentene) (PMP)-based microwell platform, leveraging its lower molecular absorption and greate...

Jun Takahashi, Hiroyuki Kato, H. Zook et al. · bioRxiv · 0 citations

Open access Jul 2026

Extracellular vesicles from cytokine-treated human pancreatic ductal cells enhance HLA class I expression in beta cells

Exposure of T1D-associated cytokines to primary human ductal cells altered cargo of secreted EVs, suggesting a previously unknown ductal cell communication pathway with a potential implication for modulating beta cells during T1D progression.

Neslihan Erdem, H. Zook, Janine C. Quijano et al. · Frontiers in Immunology · 0 citations