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Author

H. Yoshiji

2 papers indexed here

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Open access Sep 2026

Imeglimin provides dual hepatic and skeletal muscle protection in experimental MASH-associated sarcopenia.

BACKGROUND & AIMS Metabolic dysfunction-associated steatohepatitis (MASH) is frequently complicated by sarcopenia, in which mitochondrial dysfunction and inflammatory catabolic signaling are implicated. We investigated whether imeglimin, an antidiabetic mitochondrial modulator, attenuates MASH-associated muscle atrophy...

Yui Osaki, K. Kaji, N. Nishimura et al. · 0 citations
Aug 2026

Metabolic Burden and Hyperuricemia Are Associated With CKD-Related Outcomes in Individuals With and Without Steatotic Liver Disease.

AIM Although steatotic liver disease (SLD) has been associated with chronic kidney disease (CKD), it remains unclear whether CKD-related outcomes are driven by hepatic steatosis itself or by accompanying cardiometabolic abnormalities. We investigated the relative contribution of hepatic steatosis and cardiometabolic ri...

Michihiro Iwaki, Hideki Fujii, Yoshihiro Kamada et al. · 0 citations

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