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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

H. Watkins

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Open access Aug 2026

Functional analysis of TTN uORFs reveals context-dependent translational regulation

Findings indicate that uORF-mediated repression of TTN is context-dependent and not recapitulated in a disease-relevant model, which highlights the complex regulation of TTN expression and the importance of validating regulatory elements in their endogenous context.

Rosemary B. Kirk, Alexander J. Sparrow, Marta Moya-Jódar et al. · 1 citation

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