Through childhood and adolescence, profound changes to the physiology of individual neurons accompany large-scale network changes in the mammalian neocortex. These physiological changes are well understood in rodent models but far less is known in the human neocortex. Here we combine patch-clamp electrophysiology and s...
R. Kendrick, Jason K. Clark, Emmalyn S. P. Leonard et al.· bioRxiv· 0 citations
OBJECTIVE
Epilepsy surgery in tuberous sclerosis complex (TSC) is underutilized but associated with improved seizure control and better neurocognitive outcomes. Here we focus on utilization of repeated surgeries to improve seizure control.
METHODS
We performed a retrospective chart review of 62 pediatric patients wit...
Alexandria Valdrighi, Kevin Pearsson, Jurriaan M. Peters et al.· Epilepsia· 0 citations
It is suggested that repeat sEEGs may help guide effective treatment in children with multifocal epilepsy, while multifocal networks may necessitate additional sEEG evaluations and subsequent surgeries, favorable seizure outcomes can be achieved.
J. Uchitel, Olubunmi A. Fariyike, Samantha Steeman et al.· Epilepsia Open· 0 citations
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