Topical febuxostat attenuates imiquimod-induced psoriasiform dermatitis and modulates NFE2L2 (NRF2)/NLRP3 mRNA expression
Topical febuxostat demonstrated significant antipsoriatic effects in the imiquimod-induced mouse model of psoriasiform dermatitis, accompanied by improvements in oxidative stress, inflammatory cytokines, and histopathological abnormalities, which support further investigation of topical febuxostat as a potential nonste...