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Open access Oct 2026

Reconstructing Dengue Exposure Dynamics and Assessing the Public Health Impact of Vaccination Scenarios Using Mathematical Models in Brazil

Brazil experienced its worst dengue epidemic in 2024, with an increase in severe outcomes among elderly individuals, highlighting the need for vaccination strategies informed by population immunity. We reconstructed state- and age-specific immune profiles by fitting an age-structured catalytic model to dengue surveilla...

Y. Ko, C. Santos, A.-T. Huang et al. · 0 citations
Open access Jul 2026

Dengue Vaccines: The Role of a Correlate of Protection in Evaluating Vaccine Safety and Risk

Dengue remains a significant global health challenge, with over half the world’s population at risk and incidence is rising. Vaccines could play an important role in controlling dengue, but without a validated correlate of protection (CoP), vaccine development relies on large, costly, and complex Phase 3 field efficacy...

J. Wong, Parker K Acevedo, Steve Whitehead et al. · 0 citations

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