Open access
Sep 2026
Enhancing the efficacy of siRNA Antibody Oligonucleotide Conjugates (AOCs) through chemical design
Antibody-oligonucleotide conjugates (AOCs) offer a promising solution to delivery challenges of therapeutic oligonucleotides. However, the relationship between their complex chemical architectures and biological activity remains poorly understood, limiting the development of important structure-function relationships....
O. Hayes, J. Rädler, E. Filipiak et al.
· bioRxiv · 0 citations