Author

H. S. dos Santos

3 papers indexed here

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Review Open access Sep 2026

Hydrogel-based strategies for the controlled delivery of analgesic and anti-inflammatory drugs

In clinical practice, drug encapsulation is an important strategy for enhancing therapeutic efficacy and reducing adverse effects. This review critically examines how polymer origin, crosslinking strategy, swelling behavior, degradation rate, and three-dimensional network architecture influence drug loading, protecti...

Jéssica Híade Silva Cristino, J. M. Guedes, Alexander Sachse et al. · Chemické zvesti · 0 citations

Open access Aug 2026

In Vitro and In Silico Evaluation of the Potentiating Effect of Thiadiazine Derivatives Against Multidrug-Resistant (MDR) Bacterial Strains

Although the evaluated thiadiazine derivatives lacked direct antibacterial activity, they significantly enhanced the efficacy of antibiotics against multidrug-resistant bacteria.

E. D. da Silva, I. G. P. Dantas, Matheus dos Santos Lourenço et al. · Antibiotics · 0 citations

Open access Jul 2026

Evaluation of Chalcone (E)‑3-(4-Fluorophenyl)-1-(2-hydroxy-3,4,6-trimethoxyphenyl)-prop-2-en-1-one against Trypanosoma cruzi (Y Strain): In Vitro Assay, In Silico Drug-Target Analysis, and MPO-Based Drug Likeness

The CPN4F molecule demonstrates potent in vitro efficacy against Chagas disease, outperforming BZN in molecular docking studies targeting cruzain and outperforming BZN in molecular docking studies targeting cruzain.

J. Pinto, Francisco Nithael Melo Lucio, L. R. Ribeiro et al. · ACS Omega · 0 citations