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Antifungals: mechanism of action, resistance, and therapeutic perspectives.
Fungal infections represent a growing challenge to global public health, driven by the increasing number of immunocompromised patients and the emergence of strains resistant to currently available antifungal drugs. It is estimated that more than 1.6 million deaths per year are attributable to fungal diseases and that t...
Candida tropicalis: An Emerging Opportunistic Pathogen at the Interface of Virulence, Antifungal Resistance, and Host Immune Interactions
Candida tropicalis has emerged as one of the most clinically relevant non-albicans Candida species, owing to its increasing global prevalence, high mortality associated with invasive infections, and rising rates of antifungal resistance. Although traditionally considered an opportunistic pathogen, growing evidence indi...