Author

H. Mei

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Open access Aug 2026

T-cell engager bispecific antibodies enable T cells to eliminate Multiple Myeloma by targeting tumor CD38 in combination with PD-L1

Bispecific antibodies have gradually been applied in the treatment of multiple myeloma(MM). The combination of bispecific antibodies targeting CD3 and CD28 mimics the dual-signaling system (antigen signaling and co-stimulatory signaling) of natural T cell activation, thereby significantly enhancing the anti-tumor res...

Chaofan Wang, Wanting Wang, Mo-Ran Wang et al. · Cell Death & Disease · 0 citations

Open access Jul 2026

High IL‐10 levels during CRS are negatively associated with NK‐cell recovery after CAR‐T cell therapy

Abstract Objectives Immune reconstitution following chimeric antigen receptor (CAR)‐T cell therapy remains a critical clinical challenge, and the determinants of natural killer (NK)‐cell recovery are not fully understood. Methods We longitudinally monitored natural killer (NK)‐cell recovery in 64 patients during the fi...

Xin-Di Wang, W. Luo, Ying-Ying Li et al. · Clinical & Translational Imm... · 0 citations