Open access
Oct 2026
AI-Empowered Multimodal Data Integration and Knowledge Discovery for Pharmacovigilance
Y. Li, H. Zhou, F.-Y. Yeh et al.
· medRxiv · 0 citations
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Functional architecture of rare protein coding variation across 786,871 exomes
The Kernel Allelic Series Model (KASM) is introduced, which integrates multiple functional annotations to form a kernel describing how allelic effects within a gene covary, and AlphaMissense is the single most enriched missense predictor, but a composite score doubles its enrichment.
Kangcheng Hou, H. Li, E. Nason et al.
· medRxiv · 0 citations