Endocytosis regulates receptor trafficking and signaling, yet its role in colorectal cancer (CRC) remains unclear. We analyzed transcriptomic data from 15,025 CRC tumors to evaluate gene expression in clathrin-mediated endocytosis (CME) and the endosomal sorting complexes required for transport (ESCRT) pathway. Pathway...
H. Arai, A. Elliott, Yan Yang et al.· Oncogene· 0 citations
This Review explores the dual roles of lncRNAs as oncogenes or tumour suppressors, their involvement in immune modulation, vascular remodelling and extracellular matrix dynamics, and their involvement in immune modulation, vascular remodelling and extracellular matrix dynamics.
M. Bartolini, F. Battaglin, S. Soni et al.· Nature reviews: Gastroentero...· 0 citations
Integrated, multidimensional biomarker approaches and artificial intelligence-driven interpretation of tumor and TME features are expected to guide personalized therapy, anticipate resistance, and broaden the benefit of targeted and immune-based interventions in CRC.
M. Bartolini, S. Algaze, H. Lenz· ESMO Open· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.