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Open access Sep 2026

Phenotypic clustering of atrial fibrillation patients using latent class analysis and its potential utility for ablation strategy: insights from the DIRECT-Extend and EARNEST-PVI studies

LCA identified distinct AF phenotypes associated with prognoses that stratify prognosis and predict differential responses to catheter ablation strategies and may also provide insights into heterogeneity in response to ablation strategies.

Shun Sasaki, Y. Matsuoka, A. Sunaga et al. · 0 citations
Open access Aug 2026

Longitudinal Transcriptomic Analysis Identifies Persistent Immune-Related Signature Associated With Restrictive Left Ventricular Filling Patterns After Heart Transplantation.

BACKGROUND Diastolic dysfunction is a recognized chronic allograft complication, and a restrictive left ventricular filling pattern is associated with adverse outcomes. However, the underlying pathophysiological mechanisms remain unclear. METHODS AND RESULTS This study included 32 heart transplant recipients with a n...

Kosuke Takahari, Tatsuya Shiraki, H. Kioka et al. · 0 citations

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