H. H. Nielsen

Siponimod Induces Peripheral T Cell Redistribution Without Affecting Glial Cells or Behavior in Naïve Mice

Highlights What are the main findings? Siponimod induced pronounced peripheral T cell lymphopenia and altered lymphocyte distribution across lymphoid organs, with increased splenic T cell populations. Despite readily penetrating the blood–brain barrier, siponimod did not measurably affect glial cell densities, microgli...