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H. Guchelaar

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Open access Oct 2026

Age- and sex-stratified risk for heart failure in patients with atrial fibrillation

Females with atrial fibrillation (AF) has been reported to have a higher risk of heart failure (HF) than males, although the mechanism remains unclear. This study aims to explore age- and sex-specific risks for HF in AF patients. Using data from Statistics Netherlands (Centraal Bureau voor de Statis...

Q. Cheng, C. C. Deelder, L. Laurens et al. · 0 citations
Review Open access Sep 2026

Quality indicators measuring pharmaceutical care for asthma and chronic obstructive pulmonary disease within primary care: a scoping review.

PURPOSE Despite the growing emphasis on quality improvement, an overview of quality indicators (QIs) measuring pharmaceutical care in asthma and COPD remains limited. Numerous QIs have been developed for general respiratory care, yet often designed for physician-led hospital settings rather than pharmacist-led primary...

Claire D. Visser, H. Guchelaar, M. Teichert · 0 citations
Open access Sep 2026

DPYD c.85T>C, DPYD c.496A>G, and DPYD c.2194G>A and severe toxicity to fluoropyrimidines in PREPARE and Alpe-DPD trials. An original study and meta-analysis.

Current DPYD genotyping panels used to prevent fluoropyrimidine (FL)-related toxicity explain only a limited proportion of severe adverse events. The clinical relevance, beyond current testing, of additional DPYD variants, including DPYD⁎6 (c.2194G>A, rs1801160), DPYD c.496A>G (rs2297595), and DPYD⁎9A (c.85T>C, rs18012...

E. De Mattia, J. Polesel, M. van der Lee et al. · 0 citations
Review Jul 2026

Validation of a Text-Mining Tool for Extracting Routine Clinical Care Data in Early-Stage Resectable Non-Small Cell Lung Cancer.

CTcue performance for patient selection was lower than anticipated, however, it enables accurate, efficient extraction of structured and unstructured EHR data in early-stage NSCLC.

Hanieh Abedian Kalkhoran, Tobias Martinot, Lydia H N Schonewille et al. · 0 citations

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