Background and purpose While Chimeric antigen receptor (CAR) T-cell therapy has transformed treatment of relapsed/refractory diffuse large B-cell lymphoma (DLBCL), over half of patients relapse within 1 year with poor prognosis. Salvage radiotherapy (sRT) achieves high local response rates, but which subgroups benefit...
Jia-Qi Fan, N. Kutsch, J. Heger et al.· Acta oncologica· 0 citations
Clinical data on Bundibugyo virus (BDBV) infection are limited, and no approved virus-specific treatment exists. We describe the case of a previously healthy 39-year-old healthcare worker who acquired BDBV infection while working in Ituri Province, Democratic Republic of the Congo (DRC), and was medically evacuated to...
Alexander Uhrig, Frieder Pfäfflin, P. Tober-Lau et al.· Nature Medicine· 1 citation
RNA-LNP-mediated 1-18-LS RibobNAb monotherapy of viremic HIV-1YU2-infected humanized mice resulted in durable HIV-1 suppression without emerging viral escape, a proof-of-principle for effective RNA-mediated bNAb immunotherapy of HIV-1 infection.
Sophie Sayettat, F. Tolksdorf, Robin Johannson et al.· bioRxiv· 0 citations
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