Open access
Aug 2026
ATP13A4 gates extracellular polyamine levels to control excitatory synaptogenesis
Astrocytic polyamine clearance via ATP13A4 tunes extracellular spermidine to shape synapse formation during development, showing how brain extracellular levels are controlled has remained unclear.
S. van Veen, Emily Meeus, D. Irala et al.
· Nature Communications · 1 citation