H. Degens

Nanoscale spatial confinement of proton flux by cardiolipin drives high-speed lateral proton transport in mitochondria

Cellular respiration depends on the rapid, lateral flow of protons along the inner mitochondrial membrane to drive ATP synthesis. The precise nanoscale thermodynamic forces confining protons to this “local circuit” remain highly debated. Previous attempts to model macroscopic interfacial proton diffusion have been hind...