Higher Loading Dose of Colistin for the Treatment of Ventilator-Associated Pneumonia in Critically Ill Children: A Retrospective Comparative Study at Queen Rania Abdullah Hospital for Children
Background: Ventilator-associated pneumonia (VAP) remains a significant cause of morbidity and mortality in pediatric intensive care units (PICUs), particularly when caused by multidrug-resistant (MDR) Gram-negative organisms. Colistin has re-emerged as a last-line antibiotic for these infections; however, optimal dosi...