Exploratory mediation analysis of associations between serum biomarkers of neuronal injury, astrocyte reactivity, neuroinflammation, and neurotrophic support and fatigue in Parkinson's disease
Introduction and aim. Fatigue is a debilitating non-motor symptom in Parkinson's disease (PD). This exploratory cross-sectional mediation analysis investigated whether specific serum biomarkers mediate the relationship between PD and fatigue severity. Material and methods. Ninety PD patients and 45 matched controls we...