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Author

H. Al-Ahmadie

2 papers indexed here

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Nov 2026

Location, Location, Location: Membranous Nectin-4 as a Biomarker for Enfortumab Vedotin.

Combination therapy with enfortumab vedotin, a Nectin-4-targeted antibody-drug conjugate, and pembrolizumab, an anti-PD1 antibody, recently supplanted platinum-based chemotherapy as standard first-line systemic therapy for patients with muscle-invasive or metastatic urothelial cancer. A composite biomarker integrating...

James A. Rodrigues, H. Al-Ahmadie, D. Aggen et al. · 0 citations
Open access Oct 2026

Prevalence of PD-L1-High Tumor Expression and Association with First-Line Treatment Outcomes in Patients with Metastatic Urothelial Carcinoma: Results from a Prospective Observational Cohort Study.

More than half of patients had high pretreatment tumor PD-L1 expression, and there was no significant association between PD-L1 status and ORR, PFS, or OS with any first-line therapy, although definitive conclusions cannot be made because of the limited sample size.

P. Grivas, P. Agarwal, H. Al-Ahmadie et al. · 0 citations

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