Ameliorative effects of date palm (Phoenix dactylifera L.) fruit extract on sperm quality, DNA integrity, and oxidative stress in a busulfan-induced model in rats.
Antioxidant-rich DPFE exerts a significant protective effect against busulfan-induced testicular toxicity, with its mechanism strongly linked to attenuation of testicular oxidative injury, thereby improving conventional sperm quality and, critically, preserving sperm chromatin structure and DNA integrity.