The efficacy of haploidentical hematopoietic stem cell transplantation (haplo-HSCT) in elderly patients with acute myeloid leukemia (AML) remains poorly defined.
This study aimed to assess the survival benefit of haplo-HSCT among elderly AML patients compared to chemotherapy.
AML patients more than 60...
Bing-Qian Jiang, Hai-Fei Guo, Na Tao et al.· Therapeutic Advances in Hema...· 0 citations
Abstract Background CD19-targeting chimeric antigen receptor T-cells (CAR-T) and blinatumomab represent two leading immunotherapies for relapsed/refractory B cell acute lymphoblastic leukemia (r/r B-ALL). Despite sharing the same target, their differential clinical efficacy and underlying mechanisms remain unclear. Met...
Ke-Xin Wang, Lei Yu, Xing-Hua Liang et al.· Journal for ImmunoTherapy of...· 0 citations
The results of this nonrandomized clinical trial suggest that ultralow-dose META 10-19 demonstrated promising antitumor activity and a manageable safety profile in patients with R/R DLBCL.
Yong-Xian Hu, Ming-Ming Zhang, M. Gao et al.· JAMA Oncology· 1 citation
The initial results indicate that CD7 CAR-T cell therapy exhibits a manageable safety profile and preliminary efficacy in R/R AML patients, supporting further investigation in larger trials.
Mingming Zhang, Lianxuan Liu, Shan Fu et al.· Leukemia· 0 citations
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