Author

Guo-Wei Wei

2 papers indexed here

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Open access Aug 2025

CAKR: commutative algebra k-mer representations for genomics

Despite the availability of various sequence analysis models, comparative genomic analysis remains a challenge in genomics, genetics, and phylogenetics. Commutative algebra, a fundamental tool in algebraic geometry and number theory, has rarely been used in data and biological sciences. In this study, we introduce comm...

F. Suwayyid, Yuta Hozumi, Mushal Zia et al. · Nature Communications · 13 citations · ⚡2

Preprint Aug 2026

PSLL: Persistent Sheaf Laplacian Learning for Protein-Ligand Binding Affinity Prediction

The computational results indicate that the proposed Persistent Sheaf Laplacian learning (PSLL) model achieves strong predictive performance across benchmark datasets, highlighting its potential as an interpretable and mathematically grounded framework with promising generalizability for molecular machine learning and...

Mushal Zia, Benjamin Jones, Guo-Wei Wei · 0 citations