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Guo-Wei Wei

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Jul 2026

AlphaFunctor: Bridging The Gap Between Protein Function Annotation and Property Prediction.

AlphaFunctor is a category theory based foundation model-like platform to bridge the gap between protein function annotation and property prediction, based on the hypothesis that protein function and properties can be directly derived from protein sequence.

Xiang Liu, Anna E. Yee, J. Vermaas et al. · 0 citations
Jul 2026

Persistent Manifold Learning of Protein Properties

PML is introduced, a novel computational framework that describes a binding interface as a family of multiscale manifolds, and results indicate that much of what determines binding strength is encoded in the shape of the interface itself, and that a single geometric description serves both classes without hand-tailored...

Xingjian Xu, Zhe Su, Guo-Wei Wei et al. · 0 citations

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