Open access
Sep 2026
Overexpression of FTO inhibits ferroptosis induced by OGD/R in mouse renal tubular epithelial cells
Ischemia-reperfusion (I/R) is recognized as one of the major causes of acute kidney injury (AKI), yet its underlying mechanism remains unclear. This study aimed to investigate the molecular mechanism by which FTO alleviates AKI through activating the NRF2/SLC7A11/GPX4 pathway to inhibit ferroptosis. AKI model induc...
Xiao-Yan Su, Guo-Shun Li, Jian-Qi Liu et al.
· Scientific Reports · 0 citations