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Guo-Ming Zhang

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Open access Aug 2026

Photoreceptor-derived FGF2 mediates a protective stress response without driving pathological retinal neovascularization in ischemic retinopathy

The findings identify endogenous retinal FGF2 as a photoreceptor-derived survival factor that is induced during stress but is insufficient to drive pathological angiogenesis, and support a model in which neuronal adaptation and vascular remodeling represent partially distinct responses during ischemic retinal injury.

Zhifei Wu, Lulu Peng, Jie-Chun Wu et al. · 0 citations

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