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Aug 2026

Integrated multi-omics analysis reveals common genetic architecture between ulcerative colitis and psoriasis.

BACKGROUND Ulcerative colitis (UC) and psoriasis (PS) are both chronic inflammatory disorders that frequently occur together in clinical settings. Nevertheless, the common genetic basis and biological mechanisms underlying this comorbidity remain insufficiently understood. METHODS We integrated genome-wide associatio...

Guo Liu, Na Wu, Qing-Hua Luo et al. · 0 citations
Open access Sep 2026

Shared genetic basis and spatial cellular atlas of psoriasis and metabolic syndrome

Background Psoriasis (PS) and metabolic syndrome (MetS) frequently co-occur. Characterizing their shared genetic architecture and spatially enriched cellular populations may clarify the context of their co-occurrence and generate hypotheses for functional validation. Methods We integrated genome-wide association study...

Guo Liu, Feng-Juan Gong, Guan-Hu Yang et al. · 0 citations

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