Enhanced local neural compensation accompanied by global functional decline in Binswanger's Disease with mild cognitive impairment: loss of whole-brain integration and dynamic flexibility in resting-state networks.
The neurobiological basis of cognitive impairment in Binswanger disease remains unclear. We compared 21 Binswanger disease patients with mild cognitive impairment (BD-MCI) and 21 without cognitive impairment (BD-C) using resting-state fMRI. No healthy control group was included. All participants completed cognitive ass...