Open access
Aug 2026
Cardiomyocyte-Specific RNF128 Attenuates Pathological Cardiac Hypertrophy Progression by Stabilizing SERCA2a through Lys63-Linked Polyubiquitination
The findings of this study highlight RNF128 as a novel therapeutic target for heart failure, linking ubiquitination-dependent protein regulation to calcium handling in cardiomyocytes.
Yu-Jie Zhang, Xuehan Liu, Li-Wen Yu et al.
· Theranostics · 0 citations