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Author

Guiquan Guan

4 papers indexed here

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Open access Oct 2026

Transcriptomic analysis reveals enhanced host inflammatory responses associated with TNF-α/NF-κB signaling pathway during infection with the ASFV CN/SC/2019 pA104R-K5R.

The African swine fever virus (ASFV) is a highly contagious double-stranded DNA virus that belongs to the Asfarviridae family. Structurally, ASFV is more complex than other viruses and encodes numerous proteins within each layer. These proteins modulate viral replication in the host via a range of complex molecular mec...

Xin-Ting Lan, Yi-Kang Chen, Zhong-Hui Zhang et al. · 0 citations
Open access Sep 2026

Stage-specific proteomic and phosphoproteomic remodeling in Theileria annulata

Theileria annulata, an apicomplexan parasite, causes lymphoproliferative disease in cattle and threatens the bovine industry in tropical and subtropical regions. To clarify life-cycle mechanisms and parasite-host interactions, we conducted high-resolution Orbitrap proteomic and phosphoproteomic analyses of the schizont...

Yi-Jun Chai, Jin-Ming Wang, Jin Che et al. · 0 citations
Open access Aug 2026

Transcriptomic and Metabolomic Profiling Identifies a Core Gene–Metabolite Axis Driving African Swine Fever Virus Replication in the Soft Tick Ornithodoros lahorensis

African swine fever virus (ASFV) causes an incurable swine disease with nearly 100% mortality, posing a catastrophic threat to global pig production. The soft tick Ornithodoros lahorensis acts as a critical biological vector that sustains persistent ASFV replication and mediates long‐distance viral transmission, yet th...

Jin Luo, Kai-Fei Guo, Fang Xiao et al. · 0 citations
Open access Jul 2026

Activity of octyl gallate against drug-sensitive and buparvaquone-resistant Theileria annulata

Theileria annulata, the causative agent of tropical theileriosis, poses a significant threat to cattle industries, a challenge further intensified by increasing drug resistance. In this study, the food-grade phenolic compound octyl gallate (OG) was evaluated for its antitheilerial activity and identified as a potent an...

Jin Che, Yixuan Wu, Yikang Chen et al. · 0 citations

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