Author

Guillaume Bourque

2 papers indexed here

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Open access Oct 2026

Altered sperm DNA methylation provides an epigenetic route from overweight and older men to intergenerational disease transmission

Significance When it comes to the health of a pregnancy and the child, the mother has long been the focus. However, an accumulation of evidence from animal models indicates that a father’s health and exposures are equally important. For humans, it remains unknown how sperm carries information on a father’s health and e...

Mathieu Schulz, X. Shao, R. Lambrot et al. · Proceedings of the National... · 0 citations

Open access Sep 2026

The gene-regulatory evolution of the human skeleton

A coordinated evolutionary remodelling of the human skeletal ECM is revealed, including a marked suppression of glycosaminoglycan biosynthesis, leading to an approximately three-to-fourfold reduction in joint GAG content in humans compared with non-human apes.

Yi-Zhi Yan, Nadav Mishol, Katharina Lange et al. · Nature · 1 citation