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Gui-Hua Wang

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Open access Oct 2026

NSUN3‐Associated m5C Modification of tRF5‐GlyTCC Suppresses Colorectal Cancer Progression via RPL23‐Linked Nucleolar Stress and p53‐Associated Autophagy and Enhances 5‐FU Sensitivity

ABSTRACT tRNA‐derived small RNAs (tsRNAs) regulate gene expression and cellular stress responses in cancer, but their roles in colorectal cancer (CRC) progression and chemotherapy response remain incompletely understood. Dysregulated tsRNAs in CRC were identified by RNA sequencing. The functions of tRF5‐GlyTCC were eva...

Xin-Hui Lv, Can Tang, Fei-Yang Song et al. · 0 citations
Open access Sep 2026

SLAMF6 Enhances the Efficacy of Anti‐PD‐L1 Immunotherapy in CRC Through the STAT1/CXCL10 Signaling Axis

ABSTRACT As a T‐cell receptor co‐stimulatory protein, signaling lymphocyte activation molecule family 6 (SLAMF6) is a member of the immune cell activating receptor family and is expressed on T cells, B cells, natural killer cells (NK cells), and tumor cells. To date, the biological functions and clinical significance o...

Yu Wu, Xin-Hui Lv, Shun-Hao Zhang et al. · 0 citations
Review Open access Aug 2026

Lung Cancer Chemoresistance: Insights into the Regulatory Role of lncRNAs

This review systematically summarizes the multifaceted mechanisms through which lncRNAs influence chemoresistance across major lung cancer subtypes, particularly non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC), including regulation of cell proliferation, cell cycle progression, migration, invasion,...

Maodan Hou, Jiangyu Chen, Peng Yi et al. · 0 citations

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