Open access
Aug 2026
Targeted KRAS suppression in colorectal cancer via in vivo self-assembled siRNAs encapsulated in endogenous small extracellular vesicles.
A robust and targeted siRNA delivery system that effectively overcomes the historical limitations of KRAS targeting is established, providing a promising therapeutic strategy for a broad spectrum of KRAS-driven cancers.
Ying Sun, Yixuan Zhao, Yixuan Yang et al.
· Journal of Controlled Releas... · 0 citations