Emerging animal viruses pose persistent threats to livestock breeding and public health, underscoring the need for a deeper understanding of virus-host interactions. Nevertheless, the regulatory roles and conserved mechanisms of host non-coding RNAs (ncRNAs) during animal virus infections remain fragmented, and ncRNA-m...
Na Chen, Bao-Ge Zhang, Zi-Ding Yu et al.· Emerging Microbes and Infect...· 0 citations
Japanese encephalitis virus (JEV), a zoonotic mosquito-transmitted flavivirus, induces human encephalitis and swine reproductive diseases. No antiviral drugs or treatments exist for flavivirus infections, which cause severe symptoms. Even though some host proteins can suppress flavivirus proliferation, the virus can in...
Chen Wang, Wen-Zhen Qin, Xing-Ya Wang et al.· Veterinary Research· 0 citations
Findings identify a candidate insertion site for efficient expression of foreign antigens in the PEDV genome and provide a technical basis for the development of PEDV-based viral vector platforms.
RHuN4-F112-Cap has potential as a bivalent live-vector vaccine candidate against PRRSV and PCV2, and vaccinated piglets showed reduced DNA loads and milder lymphoid lesions after PCV2 challenge, and reduced clinical signs, lower PRRSV RNA loads, milder pulmonary lesions, and improved survival after highly pathogenic PR...
Shuolei Gao, Jiecong Yan, Juan Wang et al.· Vaccine· 0 citations
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