Author

Guang-Zhen Wu

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Review Sep 2026

N-Myristoylation: A Central Hub Integrating Tumor Signaling, Metabolism, and Immunity for Precision Therapy.

Lipid modifications are critical for membrane anchoring and signal transduction. N-myristoylation, catalyzed by NMT1/2, irreversibly attaches myristic acid to N-terminal glycine residues, enabling stable membrane localization and crosstalk with other post-translational modifications. This review traces NMT research fro...

De-Qian Xie, De-Quan Liu, Zun-Wen Zheng et al. · Medicinal research reviews (... · 0 citations

Open access Jan 2026

Single‐Cell and Machine Learning Analyses Identify MYDGF as an Immune‐Related Biomarker Associated With the Tumor Microenvironment in Clear Cell Renal Cell Carcinoma

Overall, the analyses characterize MYDGF as a microenvironment‐related biomarker linked to immune‐associated features, signaling‐associated alterations, and adverse prognosis in ccRCC and show the value of pairing single‐cell resolution with computational modeling for biomarker discovery in renal cancer.

Ying-Kun Xu, Guan-Du Li, Xin-Xiu Ren et al. · Human Mutation · 0 citations