Author

Guang Yang

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Sep 2026

Cross-target and cell-preferential CRISPR-Cas9 inhibition with carbohydrate-tagged oligonucleotides.

These findings establish sgRNA-scaffold targeting as a strategy for cross-target inhibition of Cas9 and show that carbohydrate conjugation can tune its cellular activity.

Bing-Zhi Li, Shu-Lin Wang, Min Cao et al. · Trends in Biotechnology · 0 citations